The foundation of GeneFab's mRNA success is our validated codon-optimized sequences. These are specifically engineered to perform optimally on our proprietary IVT platform, providing consistent, excellent results across a wide range of nucleic acid modifications.

However, we understand that optimal performance requires more than just sequence design. Factors like sequence design itself, the type of modified nucleic acid being used, and the NTP ratios during synthesis can significantly impact both the yield and the final quality of the mRNA.

At GeneFab, we meticulously control these reaction conditions to maximize both the amount of mRNA produced and its critical quality attributes – including its integrity, capping efficiency, and ultimately, its potency.

GeneFab IVT Reaction Optimization Work